Effect of Ginkgo biloba Extract on Cerebral Ischemia-reperfusion Injury in Rats
WANG Guangming
Guangdong Chemical and Pharmaceutical Professional College,Guangzhou 510520,China
Abstract:ObjectiveTo observe the effect of Ginkgo biloba extract(GBE) on cerebral ischemia injury in rats and explore its mechanism.MethodsRat cerebral ischemia injury model was induced by middle cerebral artery occlusion, the nerve injury symptoms were evaluated ,the infarction area and the level of SOD and MDA in serum wrer determined.ResultsGBE could improve the nerve injury symptoms,reduce the infraction area of brain and the level of MDA,increase the activity of SOD.ConclusionGBE has protective effect on cerebral ischemia injury in rats and its mechanism may be associated with antioxidant activity.
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