Abstract:ObjectiveTo study the function mechanism of the traditional medicine - Ruhesuxiao Capsules on experimental mastoplasia rat.MethodsThe progesterone and estrogen were used to set up the rat mastoplasia model . Serum hormone (E2 P PRL) was measured,the change of rat mastoplasia pathology was observed by light microscope,the expression of ER,PR in breast tissue was observed by immunohistochemical technology.ResultsCompared with the model group, the effects of treatment groups were more obvious in improving the rat's mastoplasia pathology structure,regulating the E2,P,PRL in serum,decreasing the expressions of ER ,PR in breast tissue.ConclusionRuhesuxiao Capsules can inhibit the astoplasia .It is possible that the function mechanism is related to regulating the level of hormone in serum and reducing the expressing of ER,PR in breast tissue .
Key words:Ruhesuxiao Capsule; Hyperplasia of mammary glands