Changes in Blood Superoxide Dismutase before and after Treatment of Chinese Drugs in Patients with Nephrosis
Abstract:ObjectiveTo observe the curative effect of chinese drugs for reinforcing the kidney and promoting blood circulation on nephrosis.MethodsSixty-eight cases of nephrosis were divided into treatment group and control group, the reinforcing the kidney and promoting blood circulation was applied to treatment group on the base of control group treatment.Then changes of serum superoxide dismutase (SOD) and lipid perixidatio (LPO) were compared between the two groups.ResultsThe serum SOD level in nephrosis patients was lower than that in healthy children (P<0.01),but the serum levels of LPO were higher in nephrosis patients than in healthy children (P<0.01). After four-week treatment, the serum level of SOD increased obviously(P<0.01). The serum levels of LPO decreased obviously in treatment group. There were significant difference between the two group(P<0.01). ConclusionChinese drugs forreinforcing the kidney and promoting blood circulation can increase the activity of SOD to antagonice peroxide-induced damage, and therefore can treat the weakness of kidney.
Key words:Nephrosis; Reinforcing the kidney and promting blood circulation; Superoxide dismutase