Abstract:ObjectiveTo further study the safety of DuYiwei Dripping Pill and to observe the general pharmacological effects for the reference of clinical therapy. MethodsTo observe the effects of DuYiwei Dripping Pill on Bealge canine blood pressure,respiratory and ECG. In the state of paralysis, and the effects of DuYiwei Dripping Pill on rats central and somatic motion nerves. ResultsWithin a dose of 516mg/kg, it had no obvious action on canine cardiovascular systems and respiratory system. Within a dose of 688mg/kg, it didn' t inhibit the central nervous system (CNS) of rats clearly, and it didn' t affect the harmonious motion of rats' function either.ConclusionThe result indicates that within the above-mentioned dose of DuYiwei Dripping Pill, it has no effect on animal' s cardiovascular systems, respiratory system and CNS. It exerts that the systematic side of DuYiwei Dripping Pill is little.
Key words:DuYiwei dripping pill; Pharmacological effects; Cardiovascular systems; Respiratory systems; Central nervous system