Study on Extraction Technology of Qinxuan Capsules
Abstract:ObjectiveTo seek optimum extraction conditions of Qinxuan Capsules by studying on extraction process. MethodsThe optimum extraction regards baicalin as the index. It was investigated by the orthogonal design and determined by HPLC. ResultsThe influence of water consumption, draw number of times had remarkable difference (P<0.05). ConclusionThe optimum extraction process of Qinxuan Capsules obtained is that sliced medicinal herbs are extracted, with water for 3 times, with the solvent volume 8 times amount and extraction time 1 hours each time.
2.2.1 按处方取符合《中国药典》规定的各味药材共100 g,正交试验设计以提取的黄芩苷含量为考察指标,对加水量(A)、提取次数(B)、提取时间(C)等指标进行考察。加水量A:最少加水量为浸过药材药面的量。提取次数B:按分配原理,取2,3,4次3个水平。提取时间C:依经验,取1.0,1.5,2.0 h 3个水平。