Guangxi Traditional Chinese Medical University, Nanning,Guangxi 530001,China
Abstract:ObjectiveTo research the analgesic and anti-inflammative action of Melastoma dode candrum Lour, and to provide scientific experiment evidence for clinical applications.MethodsThe analgesic effect of Melestoma dode candrum Lour was obseved in the response of writhes and hot-plate tests.The anti-inflammatory effect of Melastoma dode candrum Lour was observed in inflammation models caused by dimethy benzene and in models with reinforce permeability of abdominal cavity caplillary caused by acetic acid in mice; the capillary method and glass plate method were used to determine the clotting-time of mice. Results Melastoma dode candrum Lour had a prominent analgesia effect, and restained the capillary permeability resulted from inflammation,auricle's swell by dimethybenzene.But showed no obvious effect in the clotting-time of mice.ConclusionMelastoma dode candrum Lour has remarkable effects of anti-inflammation and analgesia on experiment mice.